Similarly, glucosylceramide and glucosylsphingosine that are stored in the CNS, among other organs, in Gaucher disease type 2 and 3 caused by biallelic GVs in the GBA1 gene [73] may act as protumorigenic agents to increase the risk of glioblastoma and other tumors. Here, GBA1 is linked to Gaucher disease type 2.