Compared to age- and gender-matched HC, FD patients displayed significantly elevated levels of VEGF (pg/ml, 67.3 [39.5–118.0] vs. 0.7 [0.0–2.1], p < 0.001), ICAM-1 (ng/ml, 159.5 [78.6–333.6] vs. 0.0 [0.0–244.1], p = 0.039) and VCAM-1 (ng/ml, 48.9 [30.9–68.0] vs. 0 [0.0–25.2], p = 0.0011). The gene discussed is VEGFA; the disease is Fabry disease.