Additionally, in light of evidence linking the CXCL10/CXCR3 axis to proinflammatory and T-cell-mediated responses in cardiac diseases, our finding of elevated CXCL10 in patients may suggest a potential role for CXCL10-mediated inflammation in the pathogenesis of cardiac complications in this cohort50. The gene discussed is CXCR3; the disease is heart disorder.