Darzi et al [23] conducted a meta-analysis that included 17 studies, which indicated that VTE may be associated with the following factors: advanced age, elevated C-reactive protein levels, increased D-dimer and fibrinogen levels, tachycardia, thrombocytosis, leukocytosis, fever, leg swelling, malignancy, immobility, infection, and so on. This evidence concerns the gene CRP and thrombocytosis disease.