Among viral infections, MxA levels were significantly higher in viral-mono-detected (136.3 ng/ml; IQR, 85.7–193.5 ng/ml) than viral-mixed-detected group (69.0 ng/ml; IQR, 18.7–167.1 ng/ml; p < 0.001) (Supplementary Figure 4 and Supplementary Table 3). Here, MX1 is linked to viral infectious disease.