Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis revealed that these genes were mainly enriched in pathways related to Wnt, phosphatidylinositol 3-kinase (PI3K)–Akt, and mitogen-activated protein kinase (MAPK) signaling (Fig. 3G), which play critical roles in cancer progression. This evidence concerns the gene WNK2 and cancer.