While both genes showed elevated expression in keloids (log2FC > 1), only TNFRSF9 reached statistical significance (p = 0.0091 vs p = 0.1 for AMPH) in the testing cohort GSE44270 (n = 12; 9 keloid and 3 normal) (Fig 6A). The gene discussed is TNFRSF9; the disease is keloid.