Furthermore, compared with that of the STI/PS group, the expression of Cox-2 mRNA was significantly suppressed in all three STI/GL groups (STI/GL 0.0065%; p = 0.0022, STI/GL 0.033%; p = 0.0055, and STI/GL 0.33%; p = 0.0369) (Fig 11C). Here, PTGS2 is linked to sexually transmitted disease.