For example, during pneumococcal pneumonia, AM apoptosis can be induced by high numbers of bacteria (9) or, in a manner similar to the findings by Malainou et al. (8), by neutrophil-derived TNFSF10 (also known as TRAIL) binding to TNFRSF10B (also known as DR5) on AMs (10). Here, TNFRSF10B is linked to pneumococcal pneumonia.