FBXO11 and Decreased total neutrophil count: We did not see changes in the multipotent stem cell compartment of the BM (Figure 6K); however, the Fbxo11+/– mice showed a reduction in immunophenotypically defined granulocyte-monocyte progenitor (GMP) populations, concomitant with significantly worse neutropenia in the periphery (Figure 6L, Supplemental Figure 4I, and Figure 6M).