GIPR and type 2 diabetes mellitus: Here, we consider the GLP-1RA medications that have been widely available in clinical practice for the treatment of T2D, including semaglutide, dulaglutide, liraglutide, and exenatide, as well as the dual GLP-1R/glucose-dependent insulinotropic polypeptide receptor (GIPR) agonist tirzepatide.