All Fc-fused IL-7 treatments showed significant tumor suppression compared to the Fc control (human IgG-1 Fc with LALAPG mutation), with Fc-fused Neo-7 (Q6PT45I) being the most potent, followed by Fc-fused Neo-7 (Q6P) and Fc-fused WT-IL-7 (Figure 7A, Figure 7—figure supplement 2). Here, IL7 is linked to neoplasm.