IGF1 and respiratory system disorder: Four genetically influenced immune and endocrine biomarkers (i.e., C-reactive protein [CRP], fibrinogen [Fb], white blood cell counts [WBCC], and insulin-like growth factor-1 [IGF-1]) were modelled individually, then analysed through LPA to estimate a 10-year hospitalisation risk across 12 exploratory ICD-10 disease groups, ranging from psychiatric disorders to respiratory system disorders.