MYH9 expression, meanwhile, is reported to decrease not only as a result of genetic alterations but also under conditions of chronic stress in the kidney: glomerular MYH9 expression is repressed by HIV-1 infection, and it’s also suppressed in diabetic patients/animal/podocytes treated with angiotensin 2 (Hays et al., 2012; Kang et al., 2019). Here, AGT is linked to HIV-1 infection.