We also observed a significant CASP8 sQTL in melanocyte and other GTEx eQTL datasets relevant to cancers with associations for this locus (marked by rs10804111; r2 to rs10931936 = 0.62; D’ = 1) reflecting alternative splicing events at the exon 8 to exon 9 junction. This evidence concerns the gene CASP8 and cancer.