For example, PD-1+ DCs have been identified in the tumor microenvironment (TME) in both human and animal studies (Karyampudi et al., 2016; Strauss et al., 2020; Kwiecień et al., 2022; Lim et al., 2016; Krempski et al., 2011; Wang et al., 2022b; Gordon et al., 2017). Here, PDCD1 is linked to neoplasm.