B cell receptor signaling pathway, ferroptosis, glycosaminoglycan biosynthesis, graft‐versus‐host disease, nitrogen metabolism, pantothenate and CoA biosynthesis, porphyrin metabolism, primary immunodeficiency, proteasome, and proximal tubule bicarbonate reclamation were significantly different in the FOXO1 high group. The gene discussed is FOXO1; the disease is inborn error of immunity.