TNNT2 and coronary artery disorder: ,11,12 This discrepancy may be attributed to confounding factors such as renal dysfunction, advanced age, male sex, coronary artery disease (CAD), and reduced left ventricular ejection function (LVEF), all of which influence troponin levels.13, 14, 15 Notably, renal function plays a significant role in patients with an estimated glomerular filtration rate (eGFR) < 30 mL/min per 1.73 m2 (end-stage renal disease [ESRD]), who often exhibit approximately 3-fold higher cardiac troponin T (cTnT) levels than those with an eGFR > 60 mL/min per 1.73 m2.13