CALCR and coronary artery disorder: We found that both right and left ACFs from patients with persAF have doubled levels of miR-31–5p (associated with ageing, and shown to play a role in ischemic and coronary heart diseases) (32, 33) that negatively correlated with CTR-mRNA (CALCR) expression, pointing towards a potential regulatory role for miR-31–5p on CALCR abundance.