TPH1 and cancer: The first path corresponds to an IGFL2high/NMBhigh/TCF7high/BTLA4 high population (C06c), found with elevated protein expression of CD40LG and HLA-DR, that resides predominantly within lymphoid aggregates and spatially associates with B cells, a phenotype similar to T peripheral helper cells (Tph) previously described in both cancers and autoimmune states82.