CD8A and breast cancer: Indeed, analysis of signatures derived from bulk RNA-Seq analysis of FACS-purified human breast cancer TIL subsets (CD103+ CD69+ vs CD103- CD69+)6,36 reveals that CD103 and CD69 protein expression primarily marks C15: CD8+ Tex and not C08: ZNF683+ Trm cells (Extended Data Fig. 2M-N).