CXCL13 and breast cancer: The canonical role of Tfh cells (alternately called “Tph” outside lymphoid organs) is to support B cell differentiation in germinal centers, yet we find approximately twice as many “Tfh-like” cells (PD1+ CXCL13+ BCL6+) as B cells in this breast cancer scRNA-Seq dataset (B cells = 222, Tfh-like cells = 483), raising questions about their function (Figure 1).