MUC5B and diabetic kidney disease: In particular, a putative EXD3 loss-of-function variant p.Asp555Asn (rs200080727) was associated with higher risk of DKD (OR = 8.7; P = 4.5 × 10−9), as well as the burden of 65 low frequency missense variants in the MUC5B gene (P = 6.7 × 10−9).