NFKB1 and hepatocellular carcinoma: It is noteworthy that NFKB1 is the principal hub of thehepatocyte apoptosis network in HCC (Table 4) and a keyprotein in the network that activates expression of genesinvolved in hepatocyte apoptosis (Fig. 2), which, accordingto ANDSystem, can activate a number of anti-apoptoticgenes, including BCL2 and MCL1.