In addition, networkreconstruction and analysis identified several key genes(NFKB1, MMP9, BCL2, A4, CDN1A, CDK1, ERBB2, G3P,MCL1, FOXO1) that both display differential expression inmalignant versus healthy hepatocytes and function as hubsof the hepatocyte apoptosis network in HCC. The gene discussed is ERBB2; the disease is hepatocellular carcinoma.