ERBB2also appears to activate expression of the anti-apoptotic genesNFKB1, AKT2, and MCL1 (Fig. 1), which are downregulatedin malignant hepatocytes according to our scRNA-seq data.Thus, ERBB2 is an important potential node in the regulationof apoptosis in hepatocytes, and changes in its expressionmay contribute to HCC development. This evidence concerns the gene MCL1 and hepatocellular carcinoma.