PLAT and Stroke: Unfortunately, both therapies can only be introduced within a narrow therapeutic window: (3-4.5 hours after the stroke event) for tPA (Bluhmki et al., 2009), which effectively applies to only 1-8% of stroke patients (Dhaliwal et al., 2019), and 6 hours for EMT, which can be further expanded till 24 hours for a narrow group of selected patients (Zivelonghi and Tamburin, 2018).