GSDMD and aneurysm: On the mRNA level, aneurysm induction also stimulated the expression of inflammasome components Caspase-1 [sham: 1.0 (95% CI: 0.9–1.1) vs. aneurysm: 1.4 (95% CI: 1.0–2.8) relative expression units, p = 0.002, n = 5–6 each], IL-1β [sham: 0.9 (95% CI: 0.5–1.5) vs. aneurysm: 6.8 (95% CI: 0.1–23.3) relative expression units, p = 0.02, n = 5–6 each], and Gasdermin D [sham: 1.0 (95% CI: 0.9–1.1) vs. aneurysm: 1.4 (95% CI: 0.7–2.9) relative expression units, p = 0.02, n = 5–6 each] (Figure 2).