In head and neck squamous carcinoma (HNSCC), HPV‐induced O‐GlcNAcylation at ULK1 Ser409 antagonises PKCα‐mediated Ser423 phosphorylation, blocks chaperone‐mediated degradation, stabilises ULK1, enhances STX17 binding and ultimately promotes autophagosome–lysosome fusion.75 The gene discussed is ULK1; the disease is head and neck squamous cell carcinoma.