To study whether SNX3 causes PF, AT2 cell specific Snx3-cTg mice were produced by crossing Snx3 transgenic mice with C57BL/6JSmoc-Sftpcem(IRES-CreERT2)Smoc mice and given tamoxifen to induce CreERT2 recombinase expression at 2 months of age (Fig. 3A and Fig. S7A–G). Here, SNX3 is linked to pemphigus foliaceus.