The epithelial component exhibited overexpression of canonical epithelial genes such as PAX8, CDH1, EPCAM, BCAM, WNT7A, WFDC2, S100A6, and MUC1, as well as various keratins (KRT8, KRT19) and claudins (CLDN3, CLDN4, CLDN7), all associated with epithelial identity, adhesion, and tumor progression. This evidence concerns the gene CLDN4 and neoplasm.