Similarly, tRF‐30‐JZOYJE22RR33 and tRF‐27‐ZDXPHO53KSN induce trastuzumab resistance in HER2‐positive breast cancer cells and can serve as new predictive biomarkers for trastuzumab‐resistant breast cancer.251, 252. This evidence concerns the gene ERBB2 and breast carcinoma.