GI involvement in breast cancer is rare, occurring in only 0.2%–1.7% of clinical cases and up to 16% in autopsy series.2,3) However, ILC demonstrates a unique predilection for metastasis to the GI tract, with reported intestinal metastasis rates of 4.5%, compared with only 1.1% in IDC.4,5,10). The gene discussed is CCL27; the disease is breast cancer.