CFTR and cystic fibrosis: Lastly, individuals with clinical features that may be consistent with CF who have a sweat chloride < 30 mmol/L indicate that CF is less likely; however, it may be considered if evolving clinical criteria and/or CFTR genotyping support CF and not an alternative diagnosis, whereas a diagnosis of CFTR‐related disorder is described as a dysfunction of a singular system (i.e., pancreatitis and bronchiectasis) associated with CFTR dysfunction that does not fulfill the previously mentioned diagnostic criteria for CF.