In this study, patients in both bleeding disorder cohorts were more likely to experience recurrent miscarriages than those in the control group (≥2 pregnancy losses in 10.7%, 10.3% and 5.8% of VWD, non-VWD bleeding, and control patients, respectively, and ≥3 losses in 8%, 8.3%, and 2.9%, respectively). This evidence concerns the gene VWF and hemorrhagic disease.