MMP7 and neoplasm: Subsequently, western blot analysis was conducted to determine the changes in the levels of tumor metastasis-related proteins, including E-cadherin, N-cadherin, VEGFA, and MMP7, which showed a significant expression increase of these proteins upon AZGP1 knockdown and a decrease upon AZGP1 overexpression (Pall < 0.05; Fig. 3H).