G6PD and neoplasm: To dissect the role of the PPP in different cells within the TME, we investigated the expression levels of key enzymes in the oxidative branch of the PPP (G6PD, PGLS, and 6PGD) in tumor-infiltrating immune cells (TIICs) using a previously published single-cell RNA sequencing (scRNA-seq) dataset of TNBC (GSE161529)14.