1Cluster 0: Younger Patients with Severe Renal Dysfunction and Higher Myocardial Dyssynchrony (N = 43) was characterized by younger age (mean 58.6 ± 13.2 years), severe renal dysfunction (eGFR 12.8[8.9-19.9] mL/min/1.73m2), elevated BNP (510.0 [213.0-1075.0]pg/mL), and higher PSD (56.0[48.0-64.5]ms). The gene discussed is NPPB; the disease is Abnormal renal physiology.