Two of the genes, GFI1B and NFE2, have been implicated in blood diseases and traits (Möröy et al., 2015; Polfus et al., 2016; Jutzi et al., 2019), and in our earlier work, we identified a broad transcriptional response to inhibition of GWAS-overlapping enhancers to these genes (Morris et al., 2023). This evidence concerns the gene GFI1B and blood disease.