VPS35 and uterine corpus endometrial carcinoma: Analysis of VPS35 mutation frequency across pan-cancer revealed that uterine corpus endometrial carcinoma (5.7%), adrenocortical carcinoma (4.3%), and skin cutaneous melanoma (4.2%) exhibited the highest mutation rates, with structural variants (SV) being the most common mutation type of VPS35 (Fig. 5A).