Osteogenesis imperfecta type XI (OI-XI), is caused by a bi-allelic mutation of FKBP10 gene that results in a defect of FKBP65 protein production that leads to a delayed type I procollagen secretion and accumulation in the endoplasmic reticulum [8, 9]. This evidence concerns the gene COL1A2 and osteogenesis imperfecta.