Real-time PCR also revealed that CD206 and Arg1, the gene markers of M2 macrophages, were more highly expressed in the tumor tissues from MB-231, HeLa, HCC827 and Lm-3 cell-injected mice following UBCS039 treatment, whereas TNF-α and iNOS, the gene markers of M1 macrophages, were more highly expressed in these tissues from the mice subjected to DMSO or PBS pretreatment (Supplementary file 5). Here, TNF is linked to neoplasm.