TSSK2 and non-small cell lung carcinoma: Additionally, we identified 62 upregulated genes in nonresponder patients with NSCLC, with the top 10 most important being SPINK1, FEZF1, THBS4, BEST3, TESC, C6orf226, TSSK2, SFRP2, C1GALT1C1L, and RARRES1 (Figure 7).