However, whether in vivo synaptic density deficits are found in people with alcohol use disorder (AUD) remains unclear.METHODSThirty-two people with AUD (n = 17 women; n = 15 men) and 29 control participants (n = 17 women; n = 12 men)completed 1 PET brain imaging scan with the radiotracer [11C]UCB-J, which binds to SV2A, a marker of synaptic density. This evidence concerns the gene SV2A and alcohol abuse.