The interpretation of IgE anti‐Coronavirus remains, however, controversial: while it was shown that an immune response characterised by the production of IgE could be a biomarker for the severity of COVID‐19, including death, as patients with severe COVID‐19 had significantly higher levels of IgE targeting the SARS‐CoV‐2 nucleocapsid [11], other studies did not find such a correlation [12, 13]. The gene discussed is IGHE; the disease is COVID-19.