These data cover the unbiased cell map, which includes a rich population of ILC1/NK cells, as well as studies on the abundant helper ILC cell populations (Lin− CD127+; Lin: TCRγδ− TCRαβ− CD3− CD19− CD14− CD16− CD94− CD123− CD34− CD303− FcεRI−) from CRC, adjacent tissues, and peripheral blood. This evidence concerns the gene KLRD1 and colorectal carcinoma.