The presence of fever in 59.8% of patients coupled with the relative increase in body temperature in patients with severe COVID‐19 emphasizes the hyperinflammatory nature of SARS‐CoV‐2 infection, with the systemic release of inflammatory cytokines such as interferon gamma, IL‐1, IL‐6, and TNF‐α contributing extensively to fever pathogenesis [9, 31, 33]. The gene discussed is TNF; the disease is COVID-19.