To address this issue, the Asian Working Group for Cachexia (AWGC) established the Asian criteria for cachexia: patients with chronic wasting disease and a BMI < 21 kg/m2 or weight loss >2% over the preceding 3–6 months, coupled with anorexia, diminished handgrip strength (<28 kg for males and <18 kg for females), or C-reactive protein (CRP) > 0.5 mg/dL.17 The differences between the AWGC and EPCRC criteria were the addition of anorexia, grip strength, and CRP level. The gene discussed is CRP; the disease is Cachexia.