GH1 and acromegaly: During isoglycaemic IV glucose infusion, two subjects did not reach the threshold (GH < 0.4 μg/l) for excluding acromegaly (nadir 2.68 and 0.72 μg/l) (Fig. 4) and during OGTT, one participant did not reach the threshold (nadir 0.66 μg/l)(Fig. 4b).