The patients presented some laboratory alterations associated with a worse prognosis,such as leukocytosis (in 9.4%), leukopenia (in 18.8%), lymphopenia (in 53.1%),elevated C-reactive protein (in 44.3%), elevated LDH (in 53.3%), elevated D-dimer(in 67.7%), elevated AST (in 38.5%), elevated ALT (in 53.3%), and elevatedcreatinine (in 34.6%). The gene discussed is GPT; the disease is Decreased total leukocyte count.