Hgb: Hemoglobin; WBC: White blood cell count; ESR: Erythrocyte sedimentation rate; AG: Anion gap; Cr: Creatinine; BUN: Blood urea nitrogen; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; T bil: Total bilirubin; D bil: Direct bilirubin; NT-ProBNP: N-terminal pro-B-type natriuretic peptide; TSH: Thyroid stimulating hormone; HbA1c: Hemoglobin A1c; CRP: C-reactive protein; RF: Rheumatoid factor; ANA: Antinuclear antibody; CCP: Cyclic citrullinated peptide; ACE: Angiotensin-converting enzyme; MSSA: Methicillin-sensitive Staphylococcus auerus. The gene discussed is NPPB; the disease is rheumatoid factor measurement.