Notably, alterations in the ratios of interferon gamma (IFN‐γ) and interleukin 4 (IL‐4) signify a critical disturbance in the Th1/Th2 balance, which is essential in the progression of allergic syndromes such as asthma and allergic rhinitis (Zissler et al. 2016). The gene discussed is IL4; the disease is asthma.