To assess the clinical significance of GIPC1, Kaplan-Meier survival analysis showed a significant association between reduced GIPC1 expression and poor OS in CRC patients with pathological stages T1 and T2 in the TCGA database (Figure 1G), suggesting that GIPC1 may function as a tumor suppressor gene (TSG) in early CRC. The gene discussed is GIPC1; the disease is colorectal carcinoma.