MET and brain neoplasm: When comparing TMB differences among different MET mutation subgroups within the brain tumor cohort, we found the similar results: the MET mutation group had a higher TMB compared to the non‐MET group (median TMB 2.83 vs. 1.89, p < 0.001) (Figure 4J); both the MET single mutation group (p < 0.001) and the MET multi mutations group (p < 0.001) had higher TMBs than the non‐MET group, with the MET multi mutations group having a higher TMB compared to the MET single mutation group (median TMB 7.55 vs. 2.83, p < 0.01) (Figure 4K).