The protective actions of Fer-1 have been demonstrated across multiple organ-injury models, including LPS-induced acute lung injury, ischemia–reperfusion injury, and ventilator-induced lung injury, primarily through suppression of oxidative stress and restoration of GPX4/SLC7A11-dependent antioxidant defenses [[18], [19], [20], [21]]. The gene discussed is SLC7A11; the disease is injury.